The goal of multiscale modeling in biology is to use structurally based physico-chemical models to integrate across temporal and spatial scales of biology and thereby improve mechanistic understanding of, for example, how a single mutation can alter organism-scale phenotypes.This approach may also inform therapeutic strategies or identify candidate
Fast and effective molecular property prediction with transferability map
Abstract Effective transfer learning for molecular property prediction has shown considerable strength in addressing insufficient labeled molecules.Many existing methods either disregard the quantitative relationship between source and target properties, risking negative transfer, or require intensive training on target tasks.To quantify transferab
Rural epidemiology of HIV positive tribal patients from Chhattisgarh in India
Objective: The primary objective was to study the epidemiology of Human Immunodeficiency Virus (HIV) positive tribal patients, and the secondary objective was to study the associated comorbidities in a tertiary care hospital in the tribal (Bastar) region of Chhattisgarh, India, between December 2006 and November 2008, and their relation to CD4 coun
Robust error estimation based on factor-graph models for non-line-of-sight localization
Abstract This paper presents a method to estimate the covariances of the inputs in Duct Cover Kit a factor-graph formulation for localization under non-line-of-sight conditions.A general solution based on covariance estimation and M-estimators in linear regression problems, is presented that is shown to give unbiased estimators of multiple variance
Acupuncture-Associated Mycobacterium massiliense and Scedosporium Infections Superimposed by Tetanus
Background.Tetanus has rarely been reported in Thailand since 1982 due to 100% tetanus vaccination coverage during the neonatal period of life.However, the reemergence of tetanus has been observed in our country during the past decade, mainly due to the increasing number of migrants traveling from neighboring countries in search of work.Acupuncture